Features
* Compact Flowpath – the ultra-compact flow path of the Centramate 500 S system allows users to operate at volumes as low as 170mL (when using a single Centramate membrane cassette), enabling high concentration factors and minimizing operating volumes
* Scalable Process Technology – designed through experience, the Centramate 500 S system meets the requirements for cGMP equipment with a comprehensive qualification and documentation package, calibrated process instrumentation, and hygienic design
* Direct Flow Measurement – the magnetic inductive flowmeter provides direct flow measurement during operation, making system operation safe, accurate, and user- friendly
* High Yield and Product Recovery – the hygienic, completely drainable flow path of the Centramate 500 S system enables high product yield, optimum product recovery, and easy cleaning
* Safety in Operation – an adjustable pressure interlock provides product and operator safety in a robust and reliable TFF system
* Pressure Independent Flow – the four-piston diaphragm pump delivers constant flow even as the system pressure increases
* Data Logging Capability – data from the process instrumentation can be exported to a PC or laptop computer via the USB port on the Centramate 500 S system
* Documentation Package
* Calibration certificates for measuring instruments
* Drawings (P&ID, Layout)
* User manual
* Electrical wiring documentation incl. certificates
* Welding documentation incl. certificates
* Supplier literature
* 3.1 certificates for product wetted parts
* FDA conformity (EPDM); CE declaration
* Generic IQ documentation
Benefits
* The graduated glass vessel provides full visibility and indication of fluid level during operation, so volumes can be closely controlled
* The positive displacement diaphragm pump provides pressure independent flow, ensuring critical parameters do not vary during concentration
* Scalable process technology makes the system ideal for scale-up and scale-down studies
* Direct flow measurement with the magnetic inductive flowmeter means accurate, safe, and simple operation
* With an interlock controlling the recirculation pump, operator and product safety is maximized
* To eliminate transcription and recording errors, the Centramate 500 S system has a built-in data acquisition system which can be connected to a PC via a USB cable